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Description:May 28,  · The reason why Alzheimer disease (AD) is more frequent in individuals with Down syndrome (DS) is not known. All recognized mutations for AD are associated with increased deposition of amyloid beta (Abeta), a peptide fragment comprising amino acids that derives from the catabolism of the amyloid precursor protein (APP) .

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Down Syndrome Pathophysiology/Risk Factors Down syndrome Massachusetts Down Syndrome Congress. About MDSC. About the MDSC Executive Director's Message Mission, Vision, Purposes.

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